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GENOS IMMUNE PLUS

Epigenetic Systemic Immune Rebalancing

the innovativ epigenetic therapy for an optimized immune system

GENOS IMMUNE PLUS

Epigenetic Systemic Immune Rebalancing
A new platform for integrative and functional immunology

Immune modulation and the improvement of the Immune response are of crucial importance in today’s world, especially in the context of global health challenges such as viral diseases, the increase in autoimmune diseases and the increase in cancer. 

GENOS Immune Plus is designed for physicians, clinics and medical centers looking for advanced approaches in:​​

  • functional oncology 

  • immune regulation 

  • post-viral medicine 

  • regenerative medicine 

  • epigenetic therapy concepts   

Information-based Epigenetic Reprogramming via Signal Transduction:

The GENOS Platform for intranuclear Regulation and functional Immune Rebalancing

The GENOS method represents a first-in-class platform for information-based epigenetic regulation. By utilizing signal transduction equivalents of endogenous molecules, it enables targeted intranuclear modulation of gene expression and functional immune rebalancing. This approach introduces a novel paradigm that extends beyond conventional molecular pharmacology and may provide a foundation for future developments in oncology, regenerative medicine, and personalized healthcare.

From immune stimulation to immune intelligence

Conventional immune approaches often focus on stimulation or suppression.

GENOS focuses on something different: 

FUNCTIONAL REBALANCING

A modern immune therapy should not only activate the immune system. It should help the body regain the ability to respond intelligently, precisely and effectively. GENOS Immune Plus represents a new category in applied epigenetic regulatory medicine: “Functional Immune Reactivation through Epigenetic Signal Modulation”

The GENOS method is therefore handled as the reference and standard in functional epigenetic: It is designed to help restore functional immune competence.

The therapeutic concept focuses on:

  • restoring cellular signal transmission 

  • improving NK cell function 

  • rebalancing immune regulation 

  • supporting immune recognition 

  • improving immune responsiveness 

Immune Modulation Through Restored Cell-to-Cell Communication

GENOS IMMUNE PLUS is the first epigenetic application based on a signal transduction molecule that helps modulate the immune system in a targeted, rapid manner and—to the best of our knowledge—without side effects. Signal transduction molecules—the messengers of cellular communication—are crucial for signal transmission within cells and enable them to respond to various stimuli.

The signal transduction molecule RM31® (Regulation Molecule 31), contained in the patented GENOS process, and its role in immune modulation represent an important innovation in the regulation of CD4 and CD8, T cells as well as NK cells (natural killer cells).

RM31® is multifunctional and plays a key role not only in the immune response but also in many other epigenetic, autocatalytic positive effects. It improves cell communication and thus represents a significant innovation in medicine for addressing current immunological challenges.

THE MECHANISM
Signal Transduction as a New Level of Immune Regulation

At the core of GENOS Immune Plus lies RM31® (Regulation Molecule 31) , a signal transduction molecule integrated into the patented GENOS process in both Europe & the United States.

The GENOS mechanism encompasses:

  • modulation of intracellular signaling pathways

  • epigenetic regulation of immune-relevant gene expression

  • functional regulation of S1P receptor pathway

  • restoration of cell-to-cell communication

  • enhancement of NK cell activity and overall immune responsiveness

A new therapeutic perspective for modern medicine

GENOS Immune Plus addresses a central weakness in many chronic and severe diseases: immune dysfunction at the level of signal regulation. This makes the approach highly relevant for:

It is not the number of immune cells that defines immune strength — but their function

The Medical Challenge
When immune cells are present — but no longer effective

In oncology, autoimmune disease and post-viral syndromes, the central problem is often not the absence of immune cells — but their loss of function. Many patients show sufficient immune cell numbers. Yet functionally, the immune system may be blocked.

This is especially relevant for:

  • reduced NK cell cytotoxicity 

  • impaired IL-2 responsiveness 

  • disrupted CD4/CD8 balance 

  • chronic inflammation 

  • post-viral immune exhaustion 

  • tumor immune escape 

In oncology, this means: tumor cells may be damaged, but not effectively eliminated by the immune system. 

THE GENOS PRINCIPLE

Reactivation instead of overstimulation
GENOS Immune Plus introduces a new medical principle
functional immune reactivation instead of unspecific stimulation. 

A signal-based epigenetic approach designed to restore NK cell activity, improve immune responsiveness

and re-establish cellular communication. 

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Magistral Recipe §21 AMG (German Medical Act)

GENOS IMMUNE PLUS "READY TO USE BOX"

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Magistral Recipe §21 AMG (German Medical Act)

GENOS IMMUNE PLUS 12 vials each 7,0 ml

CLINICAL FACTS / OBSERVATIONS 
Measurable. Functional. Systemic.

Clinical immune monitoring and application observations of GENOS Immune Plus show relevant improvements in key immune parameters:

  • increased NK cell cytotoxicity 

  • improved IL-2 responsiveness 

  • CD4/CD8 immune rebalancing 

  • reduction of inflammatory activity 

  • functional immune recovery within weeks 

In documented cases, NK cell activity improved up to several-fold, with functional recovery being more relevant than immune cell count alone. 

Functional Reactivation | Epigenetic Regulation Systemic | Immune Rebalancing

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